研究方向：
1. 研究动物学习记忆过程中AMPA受体的行为和贡献，阐明神经突触可塑性及多种动物行为的生理机制。
2. 研究AMPA受体突触可塑性异常在神经精神疾病（抑郁障碍、阿尔茨海默病）发病过程中的病理作用，探索早期诊断和及时干预疾病的新策略和途径。
代表性科研论文：
1. Li JZ, Zhou RB, Wang JP, Zhang XC, Li YF, Li CY E, He B, Li Chenyang, Li Changying, Long S, Lu KJ, Liu ZD, Zhang R, Zhang C, Zhang Y*. (2025). Dynamic redistribution of AMPA receptors toward memory-related neuronal ensembles in mice barrel cortex during sensory learning. Neuron. (In press) (Research article)
2. Lu KJ, Li CY, Liu J, Wang JP, Li YF, He B, Li JZ, Zhang XC, Wei MP, Tian YL, Zhang R, Zhang C, Zhang Y*. (2023). Impairments in endogenous AMPA receptor dynamics correlates with learning deficits in Alzheimer's disease model mice. Proceedings of the National Academy of Sciences U S A. 120(40): e2303878120. (Research article)
3. Zhou R, Li J, Chen Z, Wang R, Shen Y, Zhang R, Zhou F*, Zhang Y*. (2023). Pathological hemodynamic changes and leukocyte transmigration disrupt the blood–spinal cord barrier after spinal cord injury. Journal of Neuroinflammation. 20(1):118. (Research article)
4. Ma H, Li JF, Qiao X, Zhang Y, Hou XJ, Chang HX, Chen HL, Zhang Y*, Li YF*. (2024). Sigma-1 receptor activation mediates the sustained antidepressant effect of ketamine in mice via increasing BDNF levels. Acta Pharmacologica Sinica. 45(4):704-713. (Research article)
5. Ma H, Li CY, Wang JP, Zhang XC, Li MY, Zhang R, Huang Z, Zhang Y*. (2021). Amygdala-hippocampal innervation modulates stress-induced depressive-like behaviors through AMPA receptors. Proceedings of the National Academy of Sciences U S A. 118(6): e2019409118. (Research article)
6. Chen J#, Zhang XC#, Li LP#, Ma XQ, Yang CX, Liu ZD, Li CY, Fernandez-Cabezudo M, al-Ramadi BK, Wu C, Huang WS, Zhang Y*, Zhang YH*, Liu WL*. (2021). Farnesyl pyrophosphate is a new danger signal inducing acute cell death. PLOS Biology. 19(4): e3001134. (Research article)
7. Liu Z#, Ma H#, Long S, Zhang Y*. (2022). Metabotropic Glutamate Receptor 5: a Potential Molecular Switch and Beyond. Biological Psychiatry. 92:98-99. (Invited Commentary)
